In the literature there are sporadic reports on the impact of sGAG on repair of bone tissue 15 however, their role in her recovery so far been studied extremely inadequately. It is also known that bone strength due to the presence in it of hydroxyapatite (HA). However, in the manufacture of many plastic materials HA bone is usually removed. This is to ensure that, after implantation of the organic matrix of bone was the most accessible to the processes of remodeling and bone formation of the recipient. On the other hand, if prepare materials of natural HA, they are usually quite brittle and their strength properties significantly lower than the native bone. Consequently, the strength of bone depends primarily on the structural interaction between collagen and HA 16. The article 'Osteomatriks' almost completely preserved collagen and hydroxyapatite structure of the native bone, but the materials are completely devoid of antigenicity. Great advantage of the materials 'Allomatriks-implant' and 'Osteomatriks' is the fact that they contain bone sGAG, affine-connected and with collagen and HA, which distinguishes them from those in the world of unique and greatly enhances their osteogenic potential.
It is these properties of these materials can effectively use them in cases of osteogenesis imperfecta (false joints of different etiologies, congenital bone, etc.) and other bone pathologies (dental, hand surgery, etc.) 17-20. Thus, summing up the above, we can say with confidence that the tissue bank issued CITO bioplastic materials second and third technological level, have a marked effect on the regeneration of bone tissue, have no side effects and have osteoconductive and osteoinductive properties. That is why when their clinical application received more than 93% of the positive results of treatment in patients with various pathologies of the locomotor apparatus. References: 1. Salai M., Brosh T., Keller N. et al. The effects of prolonged cryopreservation on the biomechanical properties of bone allografts: A microbiological, histological and mechanical study.