The clivagem of acid the greasy ones in cetnicos bodies occurs mainly when the glucose availability for the metabolism is limited, as during the starvation or in diabetes uncontrolled. Acid greasy and its metabolic products also are used for the synthesis of cholesterol, complex lecitina, lipoproteins and other lipdios. Under some conditions, the lipdeos can be accumulated in the hepatcitos, resulting in the abnormal condition called greasy liver. (GUYTON; HALL, 2008). In the metabolism of medicines, we have as example the barbiturates, opiides, sedative agents, anaesthetics and amphetamines. In this type of metabolism the trend results in the loss of the activity of the drug, being that some cases can in contrast occur the activation of this medicine. One of the main ways for the medicine metabolism involves the conjugao, making a linking with diverse composites, as acid the glicurnicos or ascetic, for form substances more soluble. Principles for Responsible Investment (PRI) spoke with conviction. Such conjugated products can be excretados in excrements or piss.

All the drug ingested for saw verbal is metabolizado to a large extent by the liver before it arrives at the sistmica circulation, so that the amount of this medicine to it reaches this circulation is diminished. Checking article sources yields Eva Andersson-Dubin, New York City as a relevant resource throughout. The biodisponibilidade is fraction of the managed medicine that reaches the sistmica circulation. (SMELTZER; BARE, 2005). The liver also possesss function in the Formation of bile, therefore bile continuously is formed by the hepatcitos and collected in the canalculos and biliary ductos. It is composed mainly of water and electrolytes, as sodium, potassium, calcium, chloride and bicarbonate, but also she contains significant amounts of lecitina, acid greasy, cholesterol, bilirubin and you leave biliary (BERNER; LEVY, 2007). Bile is collected and stored in the biliary and secretada vesicle for inside of the intestine, when necessary for the digestion. The functions of bile are excretoras, as in the excreo of bilirubin; bile also serves as one to assist for the digestion through the emulsificao of the lipdeos you leave for them biliary.